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Do not take Clozaril with any of the following medications:

• cisapride
• medicines for treating cancer
• mibefradil
• olanzapine
• phenothiazines like perphenazine, thioridazine and chlorpromazine
• pimozide
• ziprasidone

Clozaril may also interact with the following medications:

• caffeine
• carbamazepine
• cimetidine
• ciprofloxacin
• erythromycin or clarithromycin
• lithium
• medicines for anxiety or sleeping problems, such as diazepam or temazepam
• medicines for colds, hay fever, and other allergies
• medicines for high blood pressure
• medicines for mental depression, anxiety, or other mood problems
• nicotine
• phenytoin
• rifampin or rifabutin
• some medicines used to treat irregular heartbeats

This list may not describe all possible interactions. Give your health care provider a list of all the medicines, herbs, non-prescription drugs, or dietary supplements you use. Also tell them if you smoke, drink alcohol, or use illegal drugs. Some items may interact with your medicine.

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